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“significant reduction in the Kupperman index following 12 weeks of treatment, which was sustained throughout the 12 months of treatment”
Efficacy and safety of standard versus low-dose Femarelle (DT56a) for the treatment of menopausal symptoms.
Results:
In both groups there was a significant reduction in the Kupperman index following 12 weeks
of treatment, which was sustained throughout the 12 months of treatment (p < 0.01).
Seventy-six percent of the patients in the SD group reported a decrease in vasomotor
symptoms and seventy-eight % in the LD group (NS). This decrease was sustained following
12 months of treatment. There was no change in TSH and sex hormone levels or endometrial
thickness during the study period.
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